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Innovation by Evolution: Bringing New Chemistry to Life

Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology. In 2018, she was awarded the Nobel Prize in Chemistry for pioneering the use of directed evolution to engineer enzymes. Her research group develops evolutionary protein design methods to elucidate principles of biological design and generates novel and useful enzymes and organisms. Frances Arnold is the 2019 Van ’t Hoff Award lecturer.



Not satisfied with nature’s vast catalyst repertoire, we want to create new protein catalysts and expand the space of genetically encoded enzyme functions. We use the most powerful biological design process, evolution, to optimize existing enzymes and invent new ones, thereby circumventing our profound ignorance of how sequence encodes function.

2019 Van ’t Hoff Award lecture

Tuesday 10 December

10:15 - 11:00h




California Institute of Technology, Pasadena, USA

Research tracks

Chemistry of Life + Chemical Conversion

More information

Frances Arnold's homepage

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CHAINS 2019 is organised by NWO Domain Science with the support of partners Holland Chemistry and KNCV